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Swadeshmukul Santra

Swadeshmukul Santra

Associate Professor, University of Central Florida

Phone: (407) 882-2848

Fax: (407) 882-2819

University of Central Florida
12424 Research Parkway
Suite 400, Research Pavilion
Orlando, FL 32826, USA



Ph.D., Indian Institute of Technology Kanpur, India

Research Interests:

Nanobioimaging and sensing, cancer imaging and therapy, stem cell tracking, drug delivery, pathogen detection, nanotoxicity evaluation, study of antimicrobial nanomaterials. Projects focused on development of various nanostructured materials for applications as image contrast agents (such as fluorescent nanoparticles, magnetic nanoparticles, multimodal/multifunctional nanoparticles for probing gene expression, stem cell differentiation and other cellular functions both in vitro and in vivo), drug delivery systems (such as anti-cancer drug loaded biodegradable polymeric nanoparticles that are imageable and targetable) and antimicrobial agents.

Publications List:


    1. Banerjee S, Santra S*, "Remarkable catalytic activity of silica nanoparticle in the bis-Michael addition of active methylene compounds to conjugated alkenes", Tetrahedron Letters, 2009, 50(18), 2037-2040.
    2. Banerjee S, Kar S*, Perez, J. M., Santra S*, "Quantum dot based OFF/ON probe for detection of glutathione", Journal of Physical Chemistry C, 2009, 113 (22), 9659-9663.
    3. Kar S, Patel C, Santra S*, "Direct Room Temperature Synthesis of Valence State Engineered Ultra-Small Ceria Nanoparticles: Investigation on the Role of Ethylenediamine as a Capping Agent", Journal of Physical Chemistry C, 2009, 113 (12), 4862-4867.
    4. Biswas S, Kar S, Santra S*, Jompol Y, Arif M, Khondaker SI, "Solvothermal synthesis of high-aspect ratio alloy semiconductor nanowires: Cd1-xZnxS, a case study, Journal of Physical Chemistry C, 2009, 113(9), 3617-3624.
    5. Tallury P, Kar S, Bamrungsap S, Huang YF, Tan WH, Santra S*, "Ultra-small water-dispersible fluorescent chitosan nanoparticles: synthesis, characterization and specific targeting", Chemical Communications, 2009, (17), 2347-2349.
    6. Banerjee S, Das J, Santra S*, "Native silica nanoparticle catalyzed anti-Markovnikov addition of thiols to inactivated alkenes and alkynes: a new route to linear and vinyl thioethers", Tetrahedron Letters, 50(1), 124-127, 2009.


    1. Banerjee S, Kar S, Santra S*, "A simple strategy for quantum dot assisted selective detection of cadmium ions" Chemical Communications, (26), 3037-3039, 2008.
    2. Sharma P, Brown SC, Bengtsson N, Zhang QZ, Walter GA, Grobmyer SR, Santra S, Jiang HB, Scott EW, Moudgil BM, "Gold-Speckled Multimodal Nanoparticles for Noninvasive Bioimaging", Chemistry of Materials, 20(19), 6087-6094, 2008.
    3. Tallury P, Payton K and Santra S*, "Silica-based multimodal/multifunctional nanoparticles for bioimaging and biosensing applications" Nanomedicine, 3(4), 579-592, 2008.
    4. Kar S, Santra S*, Chaudhuri S, "Direct Synthesis of Indium Nanotubes from Indium Metal Source" Crystal Growth and Design, 8(1), 344-346, 2008.
    5. Kar S, Santra S*, Chaudhuri S, "ZnO nanotube arrays and nanotube-based paint-brush structures: A simple methodology of fabricating hierarchical nanostructures with self-assembled junctions and branches" Journal of Physical Chemistry C, 112(22), 8144-8146, 2008.
    6. Kar, S., S. Santra*, and H. Heinrich, "Fabrication of high aspect ratio core-shell CdS-Mn/ZnS nanowires by a two step solvothermal process", Journal of Physical Chemistry C, 112(11), 4036-4041, 2008.
    7. Kar S, Santra S*, Chaudhuri S, "Direct Synthesis of ZnS Nanoribbons, Micro-sheets and Tetrapods", Journal of Nanoscience and Nanotechnology, 8(6), 3222-3227, 2008.
    8. Bera D, Qian L, Sabui S, Santra S, Holloway P. H., "Photoluminescence of ZnO quantum dots produced by a sol-gel process", Optical Materials, 30(8), 1233-1239, 2008.

2005 - 2007 (Selected)

  1. Yang H, Santra S*, Walter G. A. and Holloway P. H., "GdIII-functionalized fluorescent quantum dots for multimodal imaging probes", Advanced Materials, 18, 2890-2894, 2006.
  2. Mericle RA, Richter EO, Eskioglu E, Watkins C, Prokai L, Batich CD and Santra S, "Preoperative endovascular brain mapping for intraoperative volumetric image guidance: preliminary concept and feasibility in animal models", Journal of Neurosurgery, 104, 566-573, 2006.
  3. Santra S*, Liesenfeld B, Bertolino C, Dutta, D, Cao Z, Tan W, Moudgil BM and Mericle RA: Fluorescence lifetime measurements to determine the core-shell nanostructure of FITC doped silica nanoparticles: An optical approach to evaluate nanoparticle photostability, Journal of Luminescence, 117 (1): 75-82, 2006.
  4. Santra S*, Bagwe RP, Dutta D, Stanley JT, Walter GA, Tan W, Moudgil BM and Mericle RA: Synthesis and characterization of fluorescent, radio-opaque and paramagnetic silica nanoparticles for multimodal bioimaging applications. Advanced Materials, 17(18), 2165-2169, 2005.
  5. Santra S*, Dutta D, Walter GA, Moudgil BM. Fluorescent Nanoparticle Probes for Cancer Imaging. Technology in Cancer Research and Treatment, 4(6): 593-602, 2005.
  6. Santra S*, Yang H, Stanley JT, Holloway PH, Moudgil BM, Walter G and Mericle RA: Rapid and effective labeling of brain tissue using TAT-conjugated CdS:Mn/ZnS quantum dots. Chemical Communications (25): 3144-3146, 2005.
  7. Santra S*, Liesenfeld B, Dutta D, Batich CD, Tan W, Moudgil BM and Mericle RA. Folate conjugated fluorescent silica nanoparticles for labeling neoplastic cells, Journal of Nanoscience and Nanotechnology, 5(6), 899-904, 2005.
  8. Santra S*, Yang H, Holloway PH, Stanley JT, Mericle RA: Synthesis of Water-Dispersible, Fluorescent, Radio-opaque and Paramagnetic CdS:Mn/ZnS Quantum Dots: A Multifunctional Probe for Bioimaging. J. Amer. Chem. Soc., 127(6): 1656-1657, 2005.
  9. Santra S*, Yang H, Dutta D, Stanley JT, Holloway PH, Tan W, Moudgil BM and Mericle RA: TAT conjugated FITC doped silica nanoparticles for bioimaging applications. Chem. Commun., (24) 2810-2811, 2004.